Mondia whitei (Mulondo)has been used as a traditional cure for male infertility problems for a very long time. Unlike other medicinal plants used for treatment of male infertility, Mondia whitei effects on the male reproductive system have been thoroughly researched.
Libido increasing aphrodisiacs act at the level of the central nervous system by altering specific neurotransmitter or specific sex hormone concentrations. They can be effective in both sexes, although most act through an increase in testosterone concentration and are therefore male-specific. Studies have reported that chronic treatment with Mulondo induced a significant increase in serum and testicular testosterone levels, the testicular protein content as well as sperm density. The observed increase in testicular protein content and weight may be the result of testosterone action. This increased sperm density observed in the cauda epididymis confirmed the androgenic effect of Mondia whitei. The findings of this study suggested that Mulondo (Mondia whitei) possesses sex-stimulant property thus supporting its traditional use as an aphrodisiac.
This works by reducing α-adrenergically stimulated contraction of the corpus cavernosum tissue thus relaxing the muscle. Relaxation of cavernous smooth muscle is critical for inducing and maintaining penile erection.
The ability of Mondia whitei to reduce contraction of the corpus cavernosum suggests that this plant posses a potential in the treatment of erectile dysfunction.
The potency of Mondia whitei as an aphrodisiac has not only been demonstrated through its ability to increase testosterone production but as well as Demonstrating the beneficial results found to human sperm function by enhancing total motility.